IMPORTANT INFORMATION: Elestrin™ is a prescription medicine that contains an estrogen hormone. Elestrin™ is used after menopause to reduce moderate-to-severe hot flashes.

Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are using Elestrin™. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause.

Do not use estrogen with or without progestins to prevent heart disease, heart attacks or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer and blood clots.

Do not use estrogens with or without progestins to prevent dementia.

Using estrogens with or without progestins may increase your risk of dementia, based on a study of women 65 years or older.

Do not use Elestrin™ if you have unusual vaginal bleeding; have or had cancer; had a stroke or heart attack within the past year; have or had blood clots; have or had liver problems; are allergic to any of the ingredients in Elestrin™ or if you may be pregnant or plan to become pregnant.

Tell your healthcare provider if you are breastfeeding; about all of your medical problems; about all prescription and non-prescription medicines, vitamins and supplements that you take; or if you are going to have surgery or will be on bed rest.

Possible side effects of estrogens, although less common, but serious include: breast cancer, cancer of the uterus, stroke, heart attack, blood clots, dementia, gallbladder disease and ovarian cancer.

Some of the warning signs of serious side effects include: breast lumps; unusual vaginal bleeding; dizziness and faintness; changes in speech; severe headaches; chest pain; shortness of breath; pains in your legs; changes in vision; or vomiting. Notify your healthcare provider right away if you get any of these warning signs or any other unusual symptom that concerns you.

The most common side effects that have been reported for estrogens include headache; breast pain; irregular vaginal bleeding or spotting; stomach/abdominal cramps, bloating; nausea and vomiting; or hair loss. These are not all the possible side effects of Elestrin™. For more information, ask your healthcare provider.

Elestrin™ should be used at the lowest dose possible for your treatment and only as long as needed.

It is important that you speak to your healthcare provider regularly about whether you still need treatment with Elestrin™ and about any questions or concerns that you have about Elestrin™.

Please see Package Insert for full Prescribing Information.